Late Infantile MLD Juvenile MLD Metachromatic Leukodystrophy

Types of MLD

Like many other genetic disorders that affect lipid metabolism, there are several forms of MLD, which are generally classified as Late-Infantile, Juvenile (sometimes broken into early Juvenile and Late-Juvenile and, finally, Adult-Onset  In the late infantile form, which is the most common form of MLD (50-60%), affected children begin having difficulty walking after the first year of life, usually at 15–24 months. Juvenile MLD has an onset between 3 and 10 years of age) usually beginning with impaired school performance. Adult-Onset MLD is the rarest form and commonly begins after age 16 and, in the initial stages, is often mis-diagnosed as a psychiatric disorder because of personality changes.

Late-Infantile MLD

Juvenile MLD

Adult MLD

About us

MLD Support Association UK was set up to bring hope to families in the fight to eradicate Metachromatic Leukodystrophy (MLD). Our aim is to provide support by way of shared information from people in similar circumstances who have already experienced the effects of the condition and/or any treatments available.

MLD Support Association UK

MLD Support Association UK is a
Registered Charity Number 1150542

Professor Timothy M Cox, MD, FRCP, FMedSci
Suzi Digby (Lady Eatwell) OBE
Iain Stewart MP


MLD Support Association UK
Floor 5
Amphenol Business Complex
Thanet Way

Tel: 07977 440809